I'm having the same prob as the previous poster. Other shipping methods work, but in store pickup will not. If I disable all other shipping methods and leave instore pickup enabled, I get the following during checkout:

"There were problems getting a shipping quote. Please verify the delivery and product information and try again.If this does not resolve the issue, please call in to complete your order."

I'll try deleting all the shipping modules, clearing the caches, and starting again.